HPC006  |  Optical Sensors for Point of Need Diagnostics

The proposed technology consists of optical sensors for point of need diagnostic applications. The technology offered is a range of cost-effective, scalable, and robust optical sensors from nanoparticles to colorimetric dyes suitable for clinical, food, and environmental point of need diagnostics. The optical sensors have been used to develop a wide range of diagnostic platforms such as lateral flow assays, bead assay, paper test strips, and microfluidic detection chips.

Exhibitor : Camtech Diagnostics

HPC009  |  In-Vitro Human 3D Skin Model

The technology provides testing services and product development for both commercial and non-commercial entities using the company proprietary skin models to replace many of today’s animal and cell-based toxicity testing models. The skin models are suitable for use in clinical testing, diagnostics, reconstructive industry and cosmetic surgery to validate their claims that have, thus far, currently being enforced for medical-related products. This technology aims to offers a one-stop solution to bring about a higher safety standards and a validated claim for consumer-end products.

Exhibitor : Denova Sciences

HPC014  |  High Throughput Photobioreactor

Microbial screening and culture optimization is a laborious, multifaceted and expensive procedure often taking years and millions to identify the ideal strain for specific use. This technologyt offers a high throughput, tablet-sized, low cost photobioreactor, herein referred as “PhotoBiobox”. This portable reactor can be used to isolate microalgae and optimize cultivation. 

Exhibitor : ED Research Co., Ltd.

HPC039  |  House Dust Mite and American Cockroach Allergens Detection Test Kits

House dust mites (HDM) and cockroach (CR) are sources of indoor allergens that prevailed in the environment causing human sensitization to a variety of allergic diseases. Quantitative detection of these allergens in dwellings of the allergic patients is an important measure for morbidity intervention, as reduction of the levels of the allergens thereof would lead to reduction of the allergen exposure, sensitization and clinical symptoms provocation. The researchers have developed the HDM and CR allergen detection and quantification test kits for monitoring major allergens of HDM and CR in environmental dust samples. 

Exhibitor : Mahidol University

HPC043  |  Xeno-free Umbilical Cord Serum for Stem Cell Manipulation for Medical Purposes

Stem cell holds great promise for medical therapies but xeno contamination is an limitation even various xeno-free proteins have been considered to replace animal serum. Human umbilical cord serum (hUCS) is one of the best protein for xeno-free stem cell preparation and the researchers have developed a high quality xeno-free hUCS media for multi-stem cell type manipulation suitable for commercialization. This technology offers a high quality xeno-free stem cell lines generated or cultured with hUCS media of superiority quality in cell proliferation, epigenetic stability immunosuppressive retaining and delaying senescence.

Exhibitor : Mahidol University

HPC062  |  Enhanced Storage and Distribution Solutions for Therapeutic Mammalian Cell Cultures.

The researchers have developed a technology for maintaining mammalian cell cultures in a quiescent state. This presents a unique and effective non-cryogenic cell pausing and transportation solution for short term storage and distribution problems.This short term storage and distribution solution is highly scalable and all ingredients are available in GMP grade.    

Exhibitor : Newcastle University

HPC077  |  Selective 5-Formylcytosine Chemical Labeling and Related Applications

The discovery of the Ten-eleven translocation (TET) protein-mediated oxidation of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC) and 5-carboxycytosine (5caC) revealed a new paradigm of epigenetic regulation in mammalian genomes. However, precise genome-wide detection of these modified cytosines, especially 5fC at single-base resolution remains challenging. The technology offers a set of selective chemical labelling of 5fC and provide several ready-to-use tools to analyse the genome-wide map of 5fC at single-base resolution in both bulk and single-cell samples. Such selective chemical labelling provides various effective tools for the research fields of epigenetics and nucleic acid biochemistry and potential clinical fields.

Exhibitor : Peking University

HPC078  |  The Magnetoreceptor (MagR) and it’s Applications

Magnetic sensing, or the ability to detect the Earth’s magnetic field (hereafter magnetoreception), is one of the most mysterious animal senses. The notion that animals can detect the Earth’s magnetic field was once ridiculed, but is now well-established fact. This technology offers an identified a magnetic receptor (designated as MagR) in animals as a rod-like protein complex magnetosensor. 

Exhibitor : Peking University

Integrating Microfluidic Chip Technology into Existing Laboratory Tools such as Microarray Plates

The technology developed allows a straightforward way to retrofit existing standard laboratory tools with novel microfluidic chip technology comprising acoustic actuation technology that performs additional functions which are not integrated into the laboratory tools.  The functions may include, mixing and sample pre-concentration, sample ejection to transfer of fluids into a mass spectrometer without needing to handle the fluid or use other equipment such as pipettes.  This advantageously reduces cost, increases efficiency and has the potential to reduce handling errors.

Exhibitor : RMIT University

HPC084  |  3D Bioprinting of Artificial Biological Tissue Networks

This technology offers 3D bioprinting of artificial biological tissue with branched vascular structures without using any scaffolds. These branched vascular structures are very important for vascularization and are challenging to develop in tissue and organ constructs engineering.  Here, the researchers have developed a method to bioprint tissue networks as a branched, self-supporting, scaffold-free artificial hollow artificial biological tissue and is comparable to the living tissue. 

Exhibitor : Sabanci University / Inovent Co.

HPC108  |  Engineered Arginine Depleting Enzymes as Multi-potent Anti-cancer Agents

Arginine is an essential amino acid for protein synthesis and the survival of cancer cells. This technology offers a biologic engineered arginine depleting enzyme (ADE) to treat cancer cells which carry a metabolic defect that renders them unable to synthesize arginine internally. The engineered ADE is designed to deplete the external supply of arginine, causing cancer cells to die while leaving normal cells unharmed. It is found that most cancers have a high degree of arginine-dependency and can potentially be treated with engineered ADE.

Exhibitor : The Hong Kong Polytechnic University

HPC114  |  DNA Probe Kits for the Detection of Bacterial Pathogens

Fish aquaculture is constrained by different diseases. Diagnosis is achieved through conventional methods such as microscopy, bacterial culture and biochemical tests, which are time-consuming and inaccurate. Endpoint PCR may be an alternative, however, it is limited to qualitative detection coupled with laborious post-PCR processing. The DNA Probe Kits offer an alternative approach to disease diagnosis because these comprise highly specific probes for real-time detection of bacterial pathogens and improved qPCR assay protocol that enables multi-probe, multi-amplicon length and multi-species detection in a single qPCR run. These kits are essential components of qPCR assay for rapid, accurate and safer pathogen detection.

Exhibitor : University of The Philippines

HPC116  |  Determination of Exact Time of Death

The technology offers a method related to determination of death time by watching body conductivity of cases in post-mortem period. It is provided that error margin is decreased by adding parameters that were not investigated and contribution to the solution in the legal jurisdiction in the studies in literature. This technology involves the method for photographing retinas of dead people with ophthalmoscope intermittently and investigating these photographs with image processing methods. In addition, time of death is determined with high accuracy by measuring and observing of electrical conductivity.

Exhibitor : Yildiz Technical University - Technology Transfer Office

USS051  |  Rapid and Cost Effective Multiplex Disease Detection Kit for Shrimps

Diagnosis of shrimp pathogens are mostly done using traditional single/nested PCR methods and are on monoplex format which can detect only single pathogen at any given time.  There is a market need to develop rapid user friendly multiplex assay for shrimp pathogens.  The technology presented here is a multiplex assay for shrimp pathogens that is rapid, cost effective, user-friendly, and is a single tube multiplex assay developed for detection of up to five different shrimp pathogens simultaneously using high resolution melting (HRM) principles.  

Exhibitor : Temasek Polytechnic