TECHNOLOGIES



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Cancer remains a leading disease burden on global society. Radiotherapy and chemotherapy are two of the most common approaches to treating cancers. Radiotherapy contributes to about 40% of cures, but advances in radiotherapy have been limited due to engineering constraints. Chemotherapy is used extensively in treating metastatic cancer where the cancer has spread to other parts of the body. However, for many cancers it only prolongs survival by months. Moreover, due to its highly toxic nature,...

Booth 5J05 - UniSA Ventures Pty Ltd

14-3-3 proteins act as adaptor proteins to regulate signaling pathways that promote cell proliferation and cell survival, acting as obligate dimers. The 14- 3-3ζ isoform is one of the dominant isoforms expressed in skin and is upregulated significantly in chronic, non-healing wounds such as diabetic ulcers. Furthermore, mice deficient in 14-3-3ζ exhibited rapid wound healing that was 3-fold faster than that observed in normal control mice. 14-3-3ζ acts to restrain the activation of Rho-ROCK sig...

Booth 5J05 - UniSA Ventures Pty Ltd

Lung cancer is one of the most common forms of cancer with an estimated 2.1 million new cases diagnosed every year. It is also the global leading cause of cancer-related death with 1.8 million deaths reported annually. There’s an unmet need for effective pharmacological therapies for many subtypes of lung cancer, particularly advanced disease where more than 80% of patients are diagnosed. Proteins that regulate cell survival and growth have emerged as promising drug targets for cancer therapy....

Booth 5J05 - UniSA Ventures Pty Ltd

Bladder cancer is a common form of cancer, which progresses by spreading into surrounding muscle. This advanced stage, called muscleinvasive bladder cancer (MIBC), is associated with poor prognosis due to a lack of effective treatment options. Currently, treatment is restricted to the surgical removal of cancerous tissue combined with radiotherapy and/or chemotherapy, which are both associated with severe side-effects as they affect both cancerous and noncancerous cells. In addition, determinin...

Booth 5J05 - UniSA Ventures Pty Ltd

The significance of this project is the potential to develop a new topical, non-steroidal anti-inflammatory treatment for dermatitis and psoriasis. Compounds in development are unrelated to those in current clinical use, possibly with a novel mechanism of action and improved safety profile. Topical steroids are widely used in the management of inflammatory skin conditions such as dermatitis and psoriasis. While topical steroids therapies are generally effective and well tolerated when used at l...

Booth 5J05 - UniSA Ventures Pty Ltd

Our CTC technique offers a personalised early cancer detection for patients, tracking cancer metastasis, cancer relapse, and giving prognostic information. The faster doctors can give a solid diagnosis, the more quickly they can save lives. Yet the blood-based or liquid biopsy detection of cancer has always been challenging due to the heterogeneity and small size of CTCs. Having an urgent clinical demand for a more efficient cancer-detecting method, our company has strategically designed a nove...

Booth 5K02 - Hong Kong Baptist University

Hot water extract of Lablab beans Lablab bean (Dolichos lablab Linne) which could be used for various purposes such as food, medicinal purpose, animal forage, and gardening comes from Korea, China, Myanmar, India and etc. For medicinal use, it has been used for the treatment of gastrointestinal diseases including diarrhea, weak stomach, especially indigestion and pain, poisoning, fever, and hangover. In China, lablab bean is also known as a powerful detoxifying agent to treat indigestion, ...

Booth 5G17 - Korea Institute of Oriental Medicine

Lipid systems have been widely used in drug delivery applications, however issues arise due to instability, insufficient drug loading and burst release of encapsulated drug molecules. Alternatively, established polymeric nanoparticles can control drug release and sustain circulation whilst providing higher stability in biological fluids, however, the biocompatibility is not as high as lipid systems. We have developed novel PLGAlipid hybrid (PLH) microparticles that combine the stabilising and c...

Booth 5J05 - UniSA Ventures Pty Ltd

Epidermolysis Bullosa (EB) is a genetic condition that causes skin fragility leading to chronic wounds, skin cancers, and gastrointestinal (GI) ulcerations. EB wounds are often complicated by infection, fibrosis and scarring, and their nutritional uptake is severely limited, all of which impacts on the length and quality of the lives of patients. We are developing systemically-acting neutralising antibodies that target a novel protein called Flightless – I that negatively affects wound healing. ...

Booth 5J05 - UniSA Ventures Pty Ltd

Every year one in ten people fall ill because of food-borne diseases. F&B industries are using a century old method to detect pathogens which requires a dedicated lab and take takes 5-10 days to get the results. This delay in microbial detection leads to hold-up of inventories, product recalls, disease outbreaks and even, loss of human lives. At Biopsin, we empower industries to detect pathogens almost in real-time. Moreover, our device can detect multiple pathogens in a single test with the sa...

Booth 5ZH4 - Biopsin Pte Ltd

Human immunodeficiency virus (HIV)/ acquired immune deficiency (AIDS) syndrome is a critical infectious disease throughout the world. Long-term treatment with HIV drugs can cause the propagation of drug-resistant strains of HIV-1. Searching for a new treatment to overcome this problem is an active area of innovative research. The rapid assays are needed for a novel PI discovering to replace the current sophisticated techniques. Our team member at the Faculty of Associated Medical Sciences, Chian...

Booth 5K06 - Science and Technology Park, Chiang Mai University

Cebiotex is a Barcelona‐based biotech company focused on developing biomedical nanofibers to deliver therapies locally. Our first medical need targeted is in the field of oncology: to reduce local recurrence and spreading of tumour cells, by improving local control of cancer after surgery.  For cancer patients, an optimal local control reduces local recurrence after surgery. Moreover, clinical epidemiological evidence associates local control and improved survival rates.  However, a complete ...

Booth 4M17 - Cebiotex

In the rehabilitation process, patients often do not accurately follow the instructions and exercises directed by their physiotherapists, either due to mistakes made on the part of the patient and/or their caregivers or the unwillingness of patients to completely follow these instructions. Rehabilitation treatments are also expensive, and therapists often have a high workload with limited time for each patient. To address this problem, we developed a system to monitor and detect the walking act...

Booth 5L07 - Singapore University of Technology and Design

This technology centres around  the development of bioactive peptide Adrenomedullin (AM) which consists of 52 amino acids. Pilot clinical studies suggested that AM has a remarkable regeneration effect on the intestinal mucosa of patients with refractory inflammatory bowel disease. The team is developing AM and long-acting AM derivatives (Next-generation AM) to provide novel treatment with an approach that is completely different from existing drugs.

Booth 5F05 - Japan Science and Technology Agency Singapore Office

Several cerebrospinal fluid (CSF) biomarkers have been recognized and established for AD diagnosis with a high diagnostic accuracy of over 85%. However, the collection of CSF is invasive and causes discomfort and side effects to the patients. On the other hand, the collection of blood, urine and saliva is relatively simple and non-invasive. This detection assay is an immunocomplex based approach with magnetic nanoprobe for sensitive detection of the target biomarkers. Once the target biomarker ...

Booth 5K02 - Hong Kong Baptist University

Although photodynamic therapy (PDT) has been accepted as a reliable and minimal invasive clinical treatment for cancers, the treatment efficacy is hampered by limitations in cancer cell recognition, molecular imaging, in situ monitoring and depth of light penetration. In light of these challenges, increasing attention is being directed to two-photon absorption photodynamic therapy (TPA-PDT) since near-infrared (NIR) photons can penetrate deeper into tissue and re-emit energy sharply without it b...

Booth 5K02 - Hong Kong Baptist University

Migraine is a common and most disabling disease among the working-age group. One Billion around the world are suffering from migraines. Migraine is characterized by severe head pain, nausea, vomiting, dizziness, and sensitivity to light, sound, and movement. To treat migraine successfully, the patients must avoid life-style behaviours and trigger factors, such as food, hot weather, stress that may relate to migraines. The role of taking proper migraine medication, including acute and preventive ...

Booth 5K06 - Science and Technology Park, Chiang Mai University

The global wound care market is worth USD19.8Bn in 2019 and is projected to grow to USD24.8Bn by 2024 at a CAGR of 4.5%. Emerging economies like India, China and Brazil are expected to provide a range of opportunities for players in the industry, driven by population explosion, growing healthcare infrastructure, increased diabetic population and healthcare spending (source: marketsandmarkets.com). In addition, a fast escalating aging population, where the number of persons aged 80 years or above...

Booth 5ZB15 - Celligenics Pte Ltd

EBV is a ubiquitous human herpes virus, which spreads through saliva. Infection is very common and most people become infected with EBV when they were young, but they will not develop any symptoms or symptoms that are not distinguishable from mild childhood illnesses. There is ~ 200,000 EBV-associated cancer new cases per year attributes to EBV. EBV causes both infectious mononucleosis and lymphoproliferative diseases. The oncogenic development of other cancers (e.g. nasopharyngeal cancer (NPC)...

Booth 5K02 - Hong Kong Baptist University

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