Technologies

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Treatment for Irritable Bowel Syndrome (IBS) Diseases

Technology Overview

Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder that is painful and difficult to cure. The symptoms of the disease are characterized by abdominal pain, bloating, alteration of bowel habits and stool patterns. These symptoms can be chronic or occasional and are without morphological and biochemical abnormality.

IBS patients are mainly young and middle-aged people. It is twice as common in women than in men. Epidemiological studies have reported that about 14% of the men population and 27% of the women population in the US present the symptoms of IBS. In Hong Kong, the statistics are about 13% and 21% of the men and women population respectively. IBS is one of the most common causes for visits in General Health Care and Gastroenterology outpatient clinics.

To date, there is no cure for IBS. There are several basic treatments for relieving IBS symptoms, including traditional chemical medication, dietary adjustments and psychotherapy. Lubiprostone, alosetron, rotundine, belladonna sulfamethoxazole and trimethoprim tablets are medications commonly used for managing IBS symptoms. However, these medicines exhibit strong side effects.

Technology Features, Specifications and Advantages

This invention relates to a Chinese herbal medicine composition, its extract and applications, which can effectually treat the symptoms of IBS. The composition is made from various kinds of important and effective Chinese herbal medicines. Its extract can be formulated as powders and suspensions. The composition has been experimented on animals (rats and mice) and compared with the medicines such as: Alosetron (dosage: 1mg/kg), Rotundine (dosage: 49.5mg/kg) and Xie Li Ting (dosage: 1.43mg/kg).

These results have showed the Chinese herbal medicine composition in treated animals can effectively cure visceral pain induced by rectal distension, torso pain induced by hot plate, diarrhea induced by castor oil and senna leaves. The composition can soothe the pain or discomfort caused by IBS. The experiments have shown that this composition delivers better results than placebo and other test medicine.

Potential Applications

The invention may be used to treat Irritable bowel syndrome (IBS) or other symptoms caused by functional gastrointestinal disorder including abdominal pain, diarrhea, constipation, flatus, bloating and tenesmus.

Customer Benefits

IBS is a common functional gastrointestinal disorder which affects around 10 to 20% of people worldwide. Currently, there is no treatment or drug which can effectively cure the disorder. This invention may provide an additional effective therapy option for patients with following benefits:

  • Safe Chinese medicine formula
  • Minimal side effects
  • Easy to use and convenient for storage
OVERVIEW
Contact Person

Kate Cheung

Organisation

Hong Kong Baptist University R&D Licensing Limited

Technology Category

  • Healthcare

Technology Readiness Level

Keywords

Diabetes; diabetic eye care; digital health; risk assessment; personalized medicine